Mt. Holyoke is the oldest of the seven sisters. It was founded (1837) in a time when college was only for young men and there was a prevailing idea that education caused infertility in women.
Perhaps this was a classic case of both correlation/causation confusion and self fulfilling prophesy. Maybe most men of the day thought women’s frailty could not endure big ideas and once women got more education they would no longer suffer fools… which could look a little bit like “infertility”.